AGEN Stock — Agenus Inc

Agenus Inc (AGEN)

Updated October 16, 2026.

AGEN is a Stock. Total return is -99.9% over the past 26.7 years, 856.3 points behind SPY at 756.4%.

Agenus Inc. is a clinical-stage biotechnology company developing immunotherapies for cancer and infectious diseases, including checkpoint inhibitor antibodies, vaccine adjuvants, and bispecific antibodies, with collaborations involving major pharmaceutical partners like Bristol-Myers Squibb, Gilead Sciences, Incyte, and Merck. The company does not currently have an established distribution schedule. Agenus appeals to investors with high risk tolerance seeking exposure to early-stage drug development in immuno-oncology.

AGEN performance versus SPY

Price and return data through 2026-10-16.

Total return is -99.9% over the past 26.7 years, 856.3 points behind SPY at 756.4%. Over the past year its total return — price change plus distributions reinvested — is 51.4%. Its deepest 1-year drawdown was 40.8%.

AGEN key facts

Asset type

Stock

Asset class

Equity

Inception date

02/04/2000

Distribution frequency

None

Last close

$6.04 (as of 2026-10-16)

Market cap

$272,777,973

Average volume

1028300.0

Beta

1.324

Payout ratio

0.0%

P/E ratio

2.39

Forward P/E

3.73

EPS

$2.53

How Dividend Vision calculates yield and returns

Distribution rate (the posted rate) uses calculation basis unavailable. Issuer rates can use a different denominator and date, including ex-date NAV. Trailing-12-month yield is the sum of split-adjusted cash distributions with ex-dates in the last 12 months, divided by the published price. It lags a recent raise or cut. Total return uses split-adjusted close with distributions reinvested on the ex-dividend date (a modeling convention, not the cash-settlement date) from the first stored bar on or after inception through the latest bar, compared with the same window on the benchmark. That is the security's total return, not your personal gain/loss.

Yield and safety methodology · Distribution rate methodology · Distribution Safety Score methodology

Sources and review

Primary sources: prices and distributions from Dividend Vision, derived from vendor EOD data.

Reviewed by Bert Sweet, CEO and Co-owner of Dividend Vision. Methodology: Distribution Safety Score.

AGEN risks and drawbacks

Total return has trailed SPY over the available window. The deepest 1-year drawdown on record here is 40.8%.

Who may consider AGEN — and who may not

It is a weaker fit for investors who need monthly cash flow (AGEN does not currently distribute); investors whose main goal is matching SPY total return. This is educational context, not a recommendation to buy or sell.

More on AGEN

• All tickers starting with A

Tagged: Healthcare.

Frequently asked questions