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ANVS Stock — Annovis Bio Inc
Annovis Bio Inc (ANVS)
Updated October 16, 2026.
ANVS is a Stock. Total return is -89.6% over the past 6.7 years, 246.6 points behind SPY at 157.0%.
Annovis Bio is a clinical-stage biopharmaceutical company developing drugs to treat neurodegeneration, with its lead candidate Buntanetap currently in phase 3 trials for Alzheimer's disease and open-label phase 3 trials for Parkinson's disease, alongside earlier-stage programs for traumatic brain injury, stroke, and cognitive decline. The company does not currently distribute dividends. This security appeals primarily to investors seeking exposure to early-stage drug development with potential for significant upside if clinical trials succeed, rather than those seeking current income.
ANVS performance versus SPY
Price and return data through 2026-10-16.
Total return is -89.6% over the past 6.7 years, 246.6 points behind SPY at 157.0%. Over the past year its total return — price change plus distributions reinvested — is -51.1%. Its deepest 1-year drawdown was 80.5%.
| Window | Total return | CAGR |
|---|---|---|
| 1M | -4.5% | — |
| 3M | -42.9% | — |
| 6M | -44.2% | — |
| YTD | -71.3% | — |
| 1Y | -51.1% | — |
| 2Y CAGR | — | -67.10% |
| 3Y CAGR | — | -49.10% |
| 5Y CAGR | — | -48.70% |
| Since inception (6.7 years) | -89.6% | -28.70% |
ANVS key facts
- Asset type
- Stock
- Asset class
- Equity
- Inception date
- 01/29/2020
- Distribution frequency
- None
- Last close
- $0.99 (as of 2026-10-16)
- Market cap
- $42,252,268
- Average volume
- 641400.0
- Beta
- 1.226
- Payout ratio
- 0.0%
- EPS
- $-1.72
How Dividend Vision calculates yield and returns
Distribution rate (the posted rate) uses calculation basis unavailable. Issuer rates can use a different denominator and date, including ex-date NAV. Trailing-12-month yield is the sum of split-adjusted cash distributions with ex-dates in the last 12 months, divided by the published price. It lags a recent raise or cut. Total return uses split-adjusted close with distributions reinvested on the ex-dividend date (a modeling convention, not the cash-settlement date) from the first stored bar on or after inception through the latest bar, compared with the same window on the benchmark. That is the security's total return, not your personal gain/loss.
Yield and safety methodology · Distribution rate methodology · Distribution Safety Score methodology
Sources and review
Primary sources: prices and distributions from Dividend Vision, derived from vendor EOD data.
Reviewed by Bert Sweet, CEO and Co-owner of Dividend Vision. Methodology: Distribution Safety Score.
ANVS risks and drawbacks
Total return has trailed SPY over the available window. The deepest 1-year drawdown on record here is 80.5%.
Who may consider ANVS — and who may not
It is a weaker fit for investors who need monthly cash flow (ANVS does not currently distribute); investors whose main goal is matching SPY total return. This is educational context, not a recommendation to buy or sell.
More on ANVS
Frequently asked questions
Does ANVS pay monthly?
No. ANVS does not currently distribute.
When does ANVS pay a dividend?
ANVS does not currently distribute.
How has ANVS performed?
Total return is -89.6% over the past 6.7 years, 246.6 points behind SPY at 157.0%. Over the past year its total return — price change plus distributions reinvested — is -51.1%. Its deepest 1-year drawdown was 80.5%.
Tickers
Holdings as-of date unavailable.
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